PILOT EVALUATION OF THE EFFECTS OF ONE SKIN PROTECTANT PRODUCT ON THE ANTIMICROBIAL PROPERTIES OF ONE SURGICAL SCRUB FORMULATION AND ON THE INTEGRITY OF LATEX GLOVES
December 31, 1997

Prepared by:
Daryl S. Paulson, Ph.D. and Carol Riccardi
BioScience Laboratories, INC.
300 North Willson Avenue
Bozeman, Montana 59715
(406) 587-5735

This study evaluated and compared the effects of the Protèque skin protectant product on the antimicrobial properties of one (1) 4% Chlorhexidine Gluconate surgical scrub formulation by measuring resident bacterial counts on the hands using the glove juice sampling procedure. Three (3) product-use configurations were used: a surgical scrub procedure followed by skin protectant application, skin protectant application followed by a surgical scrub procedure, and a control configuration using only a surgical scrub. Additionally, the effects of the Protèque skin protectant product on the material integrity of latex gloves were evaluated using the water-leak test. Twenty (20) human subjects were admitted into the study. Seventeen (17) subjects completed the study, at least five (5) subjects per test configuration.

No statistically significant difference between the three (3) product-use configurations was noted. The data indicate that the Protèque skin protectant product does not affect the antimicrobial properties of the 4% Chlorhexidine Gluconate surgical scrub formulation. The physical integrity of the surgical gloves used in the study was also evaluated using the glove leak test and was not significantly affected by the skin protectant product. No statistically significant difference in integrity was noted between the control and the test gloves.

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